The future home of 5 Neglected Nutrients

Robin Whittle  2024-02-16

Please see my Substack:

For now, please refer to these other pages:

Vitamin D - especially regarding the immune system, COVID-19, sepsis, Kawasaki disease and MIS/C

How much vitamin D to take - ratios of body weight with higher ratios for those suffering from obesity.

Detailed discussion of, and links to, the most pertinent research on the vitamin D compounds and the immune system, including regarding COVID-19.

Some older material on COVID-19 and vitamin D.



I don't have any material on magnesium, but please see Patrick Chambers' work:

Omega 3 fatty acids

I don't have anything specific on this, but (Google searches) omega 3 fatty acids are important for reducing excessive inflammation and for providing the best mix of phospholipids in our cells' plasma membranes - in part to provide the optimal mix of phospholipids for the operation of trans-membrane proteins and the other proteins which associate with them, and which may be known as "raft":  .


We ingest far more salt than our ancestors, but our body tries to retain it, since it was rare in the past.  We ingest far too little potassium, which was plentiful in the past.

A low potassium to sodium ratio (so a high sodium to potassium ratio) is very well established to be a serious risk factor for hypertension and stroke - and for stroke independently of blood pressure.

The entire ionic balance of all our cells would be better if we consumed around twice or more the typical 2 grams a day of potassium current diets generally provide, while generally avoiding the saltiest food.

Restless Legs Syndrome / Periodic Limb Movement Disorder/Syndrome

This very common, supposedly mysterious and hard to avoid neurological condition is easy to understand as inadequate opioidic and dopaminergic receptor activation in the inhibitory circuits of a uniquely human, soft touch activated, foot withdrawal spinal reflex circuit which has evolved to protect the soft foot arch.  (Only humans have arched feet.)

Although people with spinal injury probably can't be completely relieved of this condition, there are a variety of non-drug approaches to reducing it which do not require the involvement of the medical profession.  Doctors generally prescribe dopamine agonists, and when they stop working, opioids, both of which are exceedingly pernicious.  Dopamine agonist drugs are known to cause obsessive / compulsive gambling, shopping, bing eating and sex

Opioid receptor antagonists in coffee - decaf or not

I wrote a Letter which was published in the Journal of Caffeine Research (now the Journal of Caffeine and Adenosine Research): Beyond Caffeine: Coffee Contains Opioid Antagonists. 2015-03-06:  .  It is behind a paywall but Sci Hub has it: .

I will provide a update to it here, since my central point - that I was not aware of research which indicates that caffeine causes or worsens Restless Legs Syndrome - was wrong.  Caffeine withdrawal increases the risk of or worsens RLS, though small amounts of caffeine can, for a few hours, relieve this and so lessen any RLS symptoms caused by that withdrawal.  There is a peer reviewed article which reports cessation of RLS upon cessation of caffeine use - but I can't find it at present.

Robin Whittle  22 November  2022

Search engine bait: Vitamin D, sepsis, COVID-19, Restless Limbs Sensorimotor Disorder, sodium / potassium ratio, stroke, hypertension, high blood pressure medication.

© 2022  Robin Whittle   Daylesford, Victoria, Australia