Vitamin D - especially regarding the immune system, COVID-19, sepsis, Kawasaki disease and MIS/C
Detailed discussion of, and links to,
the most pertinent research on the vitamin D compounds and the immune
system, including regarding COVID-19.
Boron
Magnesium
Omega 3 fatty acids
I don't have anything specific on this, but (Google searches) omega 3 fatty acids are important for reducing excessive
inflammation and for providing the best mix of phospholipids in our cells' plasma
membranes
- in part to provide the optimal mix of phospholipids for the operation
of trans-membrane proteins and the other proteins which associate with
them, and which may be known as "raft":
https://www.sciencedirect.com/science/article/abs/pii/S0014299915004549. .
Potassium
We ingest far more salt than our ancestors, but our body tries to
retain it, since it was rare in the past. We ingest far too
little potassium, which was plentiful in the past.
A low potassium to sodium ratio (so a high sodium to potassium ratio)
is very well established to be a serious risk factor for hypertension
and stroke - and for stroke independently of blood pressure.
The entire ionic balance of all our cells would be better if we
consumed around twice or more the typical 2 grams a day of potassium
current diets generally provide, while generally avoiding the saltiest
food.
Restless Legs Syndrome / Periodic Limb Movement Disorder/Syndrome
This very common, supposedly mysterious
and hard to avoid neurological condition is easy to understand as
inadequate opioidic and dopaminergic receptor activation in the
inhibitory circuits of a uniquely human, soft touch activated, foot
withdrawal spinal reflex circuit which has evolved to protect the soft
foot arch. (Only humans have arched feet.)
Although people with spinal injury probably can't be completely
relieved of this condition, there are a variety of non-drug approaches
to reducing it which do not require the involvement of the medical
profession. Doctors generally prescribe dopamine agonists, and
when they stop working, opioids, both of which are exceedingly
pernicious. Dopamine agonist drugs are known to cause obsessive /
compulsive gambling, shopping, bing eating and sex
Opioid receptor antagonists in coffee - decaf or not
I wrote a Letter which was published in the Journal of Caffeine Research (now the Journal of Caffeine and Adenosine Research):
Beyond Caffeine: Coffee Contains Opioid Antagonists. 2015-03-06:
https://www.liebertpub.com/doi/10.1089/jcr.2014.0024 . It is behind a paywall but Sci Hub has it:
https://sci-hub.se/https://doi.org/10.1089/jcr.2014.0024 .
I will provide a update to it here, since my central point - that I was
not aware of research which indicates that caffeine causes or worsens
Restless Legs Syndrome - was
wrong.
Caffeine withdrawal increases the risk of or worsens RLS, though small
amounts of caffeine can, for a few hours, relieve this and so lessen
any RLS symptoms caused by that withdrawal. There is a peer
reviewed article which reports cessation of RLS upon cessation of
caffeine use - but I can't find it at present.